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Permanent failure — do not retry unchanged

Microsoft 365 550 5.7.243

This tenant is blocked from using HVE

Microsoft 365 550 5.7.243 means: this tenant is blocked from using HVE. It is a permanent failure, so do not retry it unchanged. The fix is in the sending or receiving configuration named above, not in the list. Fix that, then resend.

Microsoft 365’s exact wording

Quoted from Microsoft Learn: Email non-delivery reports and SMTP errors in Exchange Online, checked 2026-11-05. Placeholders are Microsoft 365’s own.

Provider's description

This tenant is blocked from using HVE. Contact your administrator.

Possible cause

The tenant is blocked from using HVE.

Provider's advice

Contact Microsoft support for more information.

Who sends itMicrosoft 365, Exchange Online and Outlook.com
Basic code550: Requested action not taken: mailbox unavailable (e.g., mailbox not found, no access, or command rejected for policy reasons) (RFC)
Enhanced code5.7.243: Microsoft 365-specific, not in the IANA registry. Its subject digit puts it under 5.7.0 other or undefined security status.
Permanent or temporaryPermanent (5xx)
Verifying the list prevents itNo

What the sender should do

The fix is in the sending or receiving configuration named above, not in the list. Fix that, then resend.

Would verifying the list have prevented Microsoft 365 550 5.7.243?

No

This reply is about your sending setup, the message or the receiving system, not about whether the address exists, so verifying the list will not prevent it.

Common questions

What does Microsoft 365 550 5.7.243 mean?
Microsoft 365 550 5.7.243 means: this tenant is blocked from using HVE. It is a permanent failure, so do not retry it unchanged. The fix is in the sending or receiving configuration named above, not in the list. Fix that, then resend.
Should I retry after Microsoft 365 550 5.7.243?
No. It is a permanent (5xx) failure, so the same message to the same address will fail again. Fix the cause first. The fix is in the sending or receiving configuration named above, not in the list. Fix that, then resend.
Would verifying my list have prevented Microsoft 365 550 5.7.243?
No. This reply is about your sending setup, the message or the receiving system, not about whether the address exists, so verifying the list will not prevent it.

Sources

Registry and provider wording is quoted exactly; guidance is written by the SimpleVerifier Team.

SimpleVerifier Team · Last checked against the sources 2026-11-05

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